Boris Markosian

Every founder's story has a version that's tidy in hindsight and a version that was actually lived — a longer, less linear path with detours that only look purposeful looking backward. Boris Markosian's runs across neuroscience, computational data architecture, and biological operations, and it took the better part of fifteen years to arrive at a single, persistent question: why does modern medicine reason about the body as a collection of independent parts, when the body itself so clearly doesn't work that way?

A path through both sides of the problem

Boris's background spans institutions and organizations including the Salk Institute, UCSD Moores Cancer Center, Genelux, the USC Keck School of Medicine, TriLink Biotechnologies, and Google — a combination that's unusual mostly because it crosses a divide that biomedicine and computer science don't often cross together. Time spent on the biological side built a working understanding of how signaling systems actually behave, and how often a clean, single-target hypothesis falls apart once you look closely enough at a real, dynamic biological network. Time spent on the data-architecture side, including at Google, built an equally practical understanding of how large, messy evidence bases can be structured well enough to reason over — a skill biomedicine has historically had less use for than it does now.

Neither half of that background was sufficient on its own. Biological expertise without a way to structure evidence at scale runs into the same wall every individual lab runs into: there's more relevant literature than any one person can hold in their head. Data architecture without deep biological grounding tends to produce systems that are technically impressive and biologically naive — models that optimize a metric without understanding why the metric matters. The thesis behind Instructional Biology only makes sense as the intersection of both.

Two ventures, one throughline

Before founding Instructional Biology, Boris founded Vaxenta Biotechnologies, built around a 2013 international patent application for a cancer vaccine approach, and later Placenta Products LLC, which launched the Vitamin Placenta supplement in 2020. Both were, in retrospect, earlier attempts at the same underlying idea that Instructional Biology now pursues more directly: that biological signaling molecules carry information a purely chemical or nutritional framing misses, and that taking that information seriously changes what's possible therapeutically.

Instructional Biology Inc. was formally founded on February 5, 2026, building on more than a decade of prior work. The company represents the most complete expression yet of that fifteen-year throughline — an attempt to build the reasoning infrastructure and the physical-processing discipline as one connected system, rather than as two separate bets.

What drives the work now

Boris describes the motivation in plain terms: too much of medicine's hardest-won progress arrives late, after years of trial and error that a more evidence-aware, systems-level approach might have shortened. That's not a claim that any current shortcut exists — it's a bet that better reasoning tools, applied patiently and validated rigorously, can change the odds over time. Instructional Biology is built to test that bet honestly, one evidence gate at a time.